Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 13;604(7906):517–524. doi: 10.1038/s41586-022-04618-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 11 — a, b, Same analyses as Fig. 3c, f, but using somatic mutation rates per megabase (a), or per protein-coding exome (b), rather than per genome (Methods). Leftmost panels show zero-intercept LME regressions of somatic mutation rates on inverse lifespan (1/lifespan), presented on the scale of untransformed lifespan (x axis). The y axes present mean mutation rates per species, although mutation rates per crypt were used in the regressions. Darker shaded areas indicate 95% confidence intervals (CI) of the regression lines; lighter shaded areas mark a two-fold deviation from the regression lines. Point estimate and 95% CI of the regression slope (k), fraction of inter-species variance explained (FVE), and range of ELB are provided. Rightmost panels show comparisons of FVE values achieved by free-intercept LME models using inverse lifespan and other life-history variables (alone or in combination with inverse lifespan) as explanatory variables. BW, black-and-white; N, naked; RT, ring-tailed.