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. 2022 Apr 13;604(7906):517–524. doi: 10.1038/s41586-022-04618-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 5 — Each panel presents somatic substitution burdens per genome for mutational signatures SBS1 (green), SBSB (yellow) and SBSC (purple) in a given species. For species with two or more individuals, the estimated regression lines from simple linear regression models on individual mean burdens per signature are shown. For species with three or more individuals, shaded regions indicate 95% confidence intervals of the regression lines. Harbour porpoise samples were excluded owing to unknown age of the sampled individual.