Table 2.
Pooled case-fatality ratio of non-typhoidal salmonella infection from 1971 up to 2019 by UN subregion, age group, serovar, and setting
| Pooled case-fatality ratio (95% CI) | Q statistic | I2 (95% CI) | τ2 | CFR estimates* | |||
|---|---|---|---|---|---|---|---|
| Global | 14·7% (12·2–17·3) | 1192·6 | 92·0 (90·7–93·0) | 0·102 | 97 | ||
| UN subregion | |||||||
| Africa | 17·1% (13·6–21·0) | 600·6 | 92·2 (90·4–93·6) | 0·093 | 48 | ||
| Eastern Africa | 15·8% (12·0–19·8) | 261·3 | 87·0 (82·9–90·1) | 0·078 | 35 | ||
| Middle Africa | 18·9% (14·7–23·6) | 4·6 | 34·3 (0·0–76·9) | 0·004 | 4 | ||
| Southern Africa | 33·1% (31·2–35·0) | 0 | NR | 0·000 | 1 | ||
| Western Africa | 19·9% (7·3–34·5) | 120·5 | 94·2 (90·7–96·4) | 0·204 | 8 | ||
| Americas† | 9·6% (0·0–25·1) | 21·2 | 81·1 (56·1–91·9) | 0·196 | 5 | ||
| Asia | 14·0% (9·4–19·4) | 353·6 | 91·5 (89·0–93·4) | 0·137 | 31 | ||
| Eastern Asia | 15·1% (8·1–23·1) | 191·7 | 93·7 (91·0–95·7) | 0·132 | 13 | ||
| Southeastern Asia | 15·4% (6·7–25·6) | 58 | 86·2 (75·8–92·1) | 0·119 | 9 | ||
| Southern Asia | 18·6% (9·9–28·4) | 0·9 | 0·0 (0·0–96·3) | 0·000 | 3 | ||
| Western Asia | 8·2% (0·0–24·0) | 98·4 | 94·9 (91·4–97·0) | 0·315 | 6 | ||
| Europe | 9·9% (6·4–14·0) | 37·7 | 68·2 (43·4–82·1) | 0·028 | 13 | ||
| Eastern Europe | 15·4% (3·6–32·2) | 0 | NR | 0·000 | 1 | ||
| Northern Europe | 15·2% (10·3–20·9) | 12·2 | 75·5 (32·2–91·1) | 0·157 | 4 | ||
| Southern Europe | 3·4% (0·9–7·2) | 3·1 | 0·0 (0·0–74·9) | 0·000 | 6 | ||
| Western Europe | 8·8% (0·0–36·9) | 6·8 | 85·2 (40·1–96·4) | 0·238 | 2 | ||
| Age group | |||||||
| Adults aged >15 years | 21·0% (16·6–25·7) | 67·5 | 74·8 (60·1–84·1) | 0·037 | 18 | ||
| Children aged ≤15 years | 12·0% (9·0–15·4) | 470·0 | 89·1 (86·6–91·2) | 0·102 | 52 | ||
| Mixed ages | 15·4% (10·6–20·9) | 547·9 | 95·3 (94·0–96·2) | 0·121 | 27 | ||
| Salmonella enterica serovar | |||||||
| Typhimurium | 21·6% (15·6–28·2) | 174·3 | 86·8 (81·6–90·5) | 0·087 | 24 | ||
| Enteritidis | 15·0% (10·9–19·7) | 88·5 | 71·7 (58·1–80·9) | 0·052 | 26 | ||
| Dublin | 19·1% (15·0–23·6) | 3·2 | 0·0 (0·0–75·9) | 0·000 | 6 | ||
| Setting | |||||||
| Hospital | 15·1% (12·5–17·8) | 776·5 | 88·7 (86·7–90·4) | 0·098 | 89 | ||
| Non-hospital | 9·9% (2·8–20·0) | 374·7 | 98·1 (97·4–98·7) | 0·145 | 8 | ||
NR=not reportable. I2 values were NR because only one study was available.
*
Number of estimates contributing to the pooled estimate.
†
Includes North America only.