Table 3.
Summary statistics and regression analyses results of reduced logit and OLS models
| Dependent variables | Mean (SD) | Coefficient (SE) | |
|---|---|---|---|
|
Logit model: HOC = 1; otherwise = 0 |
0.186 (0.390) | ||
|
OLS model: CET continuous |
38,957.3 (50,896.1) | ||
| Explanatory variables | Logit model | OLS model | |
| Time since HOC publication (days) | 726.2 (421.3) | 0.001*** (0.001) | |
| Conflict of interest | |||
| Yes | 0.331 (0.471) | − 0.955** (0.429) | |
| Rare disease = 1; = 0 otherwise | 12,728.5* (6664.6) | ||
| Intervention type | |||
| Educational/behavioural | 0.132 (0.339) | − 1.629** (0.800) | |
| Methodology | |||
| Observational study | 0.062 (0.242) | − 1.526* (0.863) | |
| CEA result Spain/Australia | |||
| ICER under €20k/AUS$20k | 0.397 (0.490) | 0.755** (0.364) | |
| ICER results (continuous) | 39,943.2 (96604.0) | NA | 0.015*** (0.0003) |
| Country | |||
| Spain | 0.508 (0.501) | 0.799* (0.483) | |
| Constant | − 2.941*** (0.464) | 34963.8*** (1089.3) | |
| Observations | 242 | 242 | 151 |
SD standard deviation, SE standard error, CEA cost-effectiveness analysis, CET cost-effectiveness threshold, HOC health opportunity cost, ICER incremental cost-effectiveness ratio
***p value < 0.01; **p value < 0.05; *p value < 0.1