Table 1.
Classification outcomes in the training and testing samples using A, all imaging features B, the 20 most important variables only and C, white matter diffusivity metrics alone
| Sample | Observed | Predicted | |||
|---|---|---|---|---|---|
| ALS | DC | HC | % Correct | ||
| (A) All features included | |||||
| Training | ALS | 140 | 2 | 9 | 92.7 |
| DC | 3 | 19 | 2 | 79.2 | |
| HC | 11 | 1 | 69 | 85.2 | |
| Overall percent | 60.2% | 8.6% | 31.3% | 89.1 | |
| Testing | ALS | 52 | 6 | 5 | 82.5 |
| DC | 2 | 9 | 2 | 69.2 | |
| HC | 14 | 1 | 31 | 67.4 | |
| Overall percent | 55.7% | 13.1% | 31.1% | 75.4 | |
| (B) 20 core features included | |||||
| Training | ALS | 126 | 1 | 32 | 79.2 |
| DC | 3 | 23 | 1 | 85.2 | |
| HC | 24 | 0 | 63 | 72.4 | |
| Overall percent | 56.0% | 8.8% | 35.2% | 77.7 | |
| Testing | ALS | 46 | 0 | 9 | 83.6 |
| DC | 2 | 7 | 1 | 70.0 | |
| HC | 15 | 0 | 25 | 62.5 | |
| Overall percent | 60.0% | 6.7% | 33.3% | 74.3 | |
| (C) Only white matter metrics included | |||||
| Training | ALS | 128 | 1 | 18 | 87.1 |
| DC | 0 | 24 | 0 | 100.0 | |
| HC | 16 | 0 | 70 | 81.4 | |
| Overall percent | 56.0% | 9.7% | 34.2% | 86.4 | |
| Testing | ALS | 53 | 3 | 11 | 79.1 |
| DC | 0 | 12 | 1 | 92.3 | |
| HC | 11 | 0 | 30 | 73.2 | |
| Overall percent | 52.9% | 12.4% | 34.7% | 78.5 | |
ALS amyotrophic lateral sclerosis, DC disease control, HC healthy control