Table 3.
Classification outcomes in the peri-diagnostic phase in the training and testing samples using A, all imaging features B, the 20 most important variables only and C, white matter diffusivity metrics alone
| Sample | Observed | Predicted | |||
|---|---|---|---|---|---|
| ALS | DC | HC | % Correct | ||
| (A) All features included | |||||
| Training | ALS | 76 | 5 | 9 | 84.4 |
| DC | 1 | 19 | 3 | 82.6 | |
| HC | 15 | 1 | 65 | 80.2 | |
| Overall percent | 47.4% | 12.9% | 39.7% | 82.5 | |
| Testing | ALS | 23 | 0 | 6 | 79.3 |
| DC | 2 | 11 | 1 | 78.6 | |
| HC | 11 | 0 | 35 | 76.1 | |
| Overall percent | 40.4% | 12.4% | 47.2% | 77.5 | |
| (B) 20 features included | |||||
| Training | ALS | 58 | 3 | 24 | 68.2 |
| DC | 3 | 22 | 1 | 84.6 | |
| HC | 15 | 1 | 68 | 81.0 | |
| Overall percent | 39.0% | 13.3% | 47.7% | 75.9 | |
| Testing | ALS | 26 | 4 | 4 | 76.5 |
| DC | 1 | 6 | 4 | 54.5 | |
| HC | 7 | 0 | 36 | 83.7 | |
| Overall percent | 38.6% | 11.4% | 50.0% | 77.3 | |
| (C) Only white matter metrics included | |||||
| Training | ALS | 62 | 3 | 13 | 79.5 |
| DC | 1 | 24 | 0 | 96.0 | |
| HC | 12 | 1 | 75 | 85.2 | |
| Overall percent | 39.3% | 14.7% | 46.1% | 84.3 | |
| Testing | ALS | 30 | 2 | 9 | 73.2 |
| DC | 2 | 9 | 1 | 75.0 | |
| HC | 5 | 1 | 33 | 84.6 | |
| Overall percent | 40.2% | 13.0% | 46.7% | 78.3 | |
ALS amyotrophic lateral sclerosis, DC disease control, HC healthy control