Antiviral activity and cytotoxicity of l(−)SddC. (a) Different susceptibilities of HBV variant to l(−)SddC. (b) Cell growth inhibition due to l(−)SddC of the generated HBV-producing cell lines and their parental cell line, HepG2. Values are means ± standard deviations of results from triplicate independent experiments. Symbols, +, HepG2-WT10; ▵, HepG2-SM1; ○, HepG2-DM2; ♦, HepG2.