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. 2022 Apr 20;12:22. doi: 10.1038/s41387-022-00199-y

Fig. 1. Effects of palmitate (C16:0) on the viability of rodent and human β-cells.

Fig. 1

Rat INS-1E (A) and human EndoC-βH1 (C) cells were treated with vehicle (0 µM), 125 µM, 250 µM, 500 µM or 1000 µM C16:0 for 24 h or 72 h, respectively. INS-1E (B) cells were treated with vehicle (0 µM) or 250 µM C16:0, either alone or in combination with C18:1 (250 µM) for 24 h. Cell death was estimated using vital dye staining. Dots represent individual data points and the histograms represent mean values + SD (N = 3). ***P < 0.001 relative to vehicle (0 µM).