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. 2022 Apr 20;8:30. doi: 10.1038/s41522-022-00289-w

Table 6.

Quartiles of Microbial Indicator of Periodontal Disease (MIP) in saliva and multiple measures of periodontal disease and markers of cardiometabolic health.

MIP Quartile 1 (N = 70) MIP Quartile 2 (N = 74) MIP Quartile 3 (N = 68) MIP Quartile 4 (N = 70) p-value
Attachment Loss N = 52 1.05 ± 0.093 N = 54 0.91 ± 0.095 N = 50 0.85 ± 0.092 N = 53 1.00 ± 0.095 0.6177
Probing Depth N = 52 1.72 ± 0.050 N = 54 1.81 ± 0.051 N = 50 1.85 ± 0.050 N = 53 1.87 ± 0.051 0.0305
%BOP N = 52 0.26 ± 0.018 N = 54 0.26 ± 0.018 N = 50 0.29 ± 0.017 N = 53 0.27 ± 0.018 0.3702
Faith_pd N = 51 12.08 ± 0.314 N = 54 13.10 ± 0.324 N = 50 14.43 ± 0.312 N = 53 15.28 ± 0.322 <0.0001
Meansbp N = 52 119.2 ± 1.55 N = 54 121.7 ± 1.59 N = 50 119.2 ± 1.55 N = 53 119.2 ± 1.60 0.7583
Meandbp N = 52 74.2 ± 1.18 N = 54 76.2 ± 1.21 N = 50 74.1 ± 1.18 N = 53 74.8 ± 1.22 0.9893
Glucosecrc N = 52 88.9 ± 1.01 N = 54 86.0 ± 1.02 N = 50 86.8 ± 0.99 N = 51 87.3 ± 1.03 0.3732
Insulin N = 52 7.97 ± 0.576 N = 54 7.97 ± 0.589 N = 50 7.96 ± 0.574 N = 53 7.97 ± 0.593 0.9995
HOMA-IR N = 52 0.018 ± 0.0014 N = 54 0.016 ± 0.0014 N = 50 0.017 ± 0.0014 N = 51 0.017 ± 0.0014 0.8211
HbA1c N = 52 5.35 ± 0.084 N = 54 5.39 ± 0.086 N = 50 5.35 ± 0.083 N = 53 5.24 ± 0.086 0.3920

Values represent the mean ± the standard error of the mean. Linear mixed models were used in order to control for within Pearson correlation. All models control for age, sex, race, BMI, and smoking status. Attachment Loss average attachment loss, Pocket Depth average periodontal pocket depth, %BOP percent of sites bleeding on probing, meansbp mean systolic blood pressure, meandbp mean diastolic blood pressure, glucosecrc fasting glucose, fasting insulin, HOMA-IR homeostatic model assessment of insulin resistance, HbA1C hemoglobin A1c. Bolded values represent statistically significant Pearson correlations for linear trends (p < 0.05).