Table 3.
Hepatic oxidative (MDA) and antioxidative (GSH and SOD) parameters in EAC-bearing mice after treatment with amygdalin and/or sorafenib.
| Groups | MDA (nmol/g tissue) | GSH (nmol/g tissue) | SOD (U/g tissue) |
|---|---|---|---|
| Cnt | 3.98 ± 0.11f | 6.31 ± 0.16b | 58.63 ± 1.23a |
| Amy | 4.01 ± 0.14f | 7.22 ± 0.23a | 54.09 ± 1.99a |
| SorIP | 4.08 ± 0.09f | 6.06 ± 0.19b | 55.28 ± 1.76a |
| SorOS | 4.17 ± 0.17f | 6.13 ± 0.18b | 56.21 ± 2.38a |
| Amy + SorIP | 4.12 ± 0.15f | 5.98 ± 0.14b | 54.14 ± 2.14a |
| Amy + SorOS | 4.23 ± 0.16f | 6.04 ± 0.15b | 56.82 ± 1.77a |
| EAC | 23.58 ± 0.76a | 3.23 ± 0.11e | 25.26 ± 0.54g |
| EAC + Amy | 15.37 ± 0.43b | 4.43 ± 0.13d | 32.12 ± 0.77f |
| EAC + SorIP | 10.50 ± 0.35d | 5.14 ± 0.14c | 39.32 ± 0.54d |
| EAC + SorOS | 13.51 ± 0.32c | 5.03 ± 0.15c | 36.39 ± 0.42e |
| EAC + Amy + SorIP | 7.30 ± 0.26e | 6.35 ± 0.22b | 47.05 ± 1.01b |
| EAC + Amy + SorOS | 9.76 ± 0.36d | 5.33 ± 0.16c | 42.31 ± 0.63c |
Data were presented as means ± SEM. Small (a–g) letters showed the marked change at P ≤ 0.05. The significant were expressed by dissimilar letters in the same column.