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. 2022 Mar 28;12(4):949–969. doi: 10.1007/s13555-022-00700-6

Table 4.

Sleep burden by self-reported AD severity and in matched non-AD control cohort

AD cohort
N = 4208
Matched non-AD control cohort
N = 4208
valuea
Mild AD
n = 2862
Moderate AD
n = 1177
Severe AD
n = 169
At least one sleep difficulty 1418 (49.6) 647 (55.0) 105 (62.1) 1636 (38.9) < 0.0001
Severity of sleep difficulties
 Mild 758 (26.5) 241 (20.5) 30 (17.8) 857 (20.4) < 0.0001
 Moderate 524 (18.3) 294 (25.0) 41 (24.3) 607 (14.4)
 Severe 136 (4.8) 112 (9.5) 34 (20.1) 172 (4.1)
Impact of sleep difficulties
 No impact 151 (5.3) 58 (4.9) 11 (6.5) 200 (4.8) < 0.0001
 Little impact 423 (14.8) 145 (12.3) 19 (11.2) 482 (11.5)
 Mild impact 376 (13.1) 171 (14.5) 18 (10.7) 451 (10.7)
 Moderate impact 349 (12.2) 214 (18.2) 38 (22.5) 392 (9.3)
 Severe impact 119 (4.2) 59 (5.0) 19 (11.2) 111 (2.6)

AD atopic dermatitis

Data reported as n (%)

aAD cohort (mild, moderate, or severe) versus matched non-eczema control cohort