Atopic dermatitis (AD) is a chronic inflammatory skin disease, and prevalence rates have increased in most countries across Europe

Although prior studies using data from the National Health and Wellness Survey have described the burden of moderate-to-severe AD, data assessing the impact of mild-to-moderate AD are limited

The objective of this study was to describe the clinical and humanistic burden of AD in Europe across severity levels, including also milder forms of this chronic disease

Respondents with mild-to-moderate AD had a higher burden of comorbidities, sleep difficulties, and psychological disorders (anxiety and depression) and poorer quality of life/functional status, work productivity, and activity levels compared with non–AD-matched controls. Additionally, the most common comorbidities observed in milder patients were consistent with those also found to be the most common in more severe AD

Results from this study highlight the importance of improving disease management across patients with varying levels of severity, including patients with only mild disease