Table 3.
Multivariable analyses of risk factors for leakage after ileostomy closure*
| Variable | Hazard ratio | 95% confidence interval | P |
|---|---|---|---|
| Age ≥65 (years) | 0.271 | 0.091–0.809 | 0.019 |
| Sex, male | 0.382 | 0.122–1.195 | 0.098 |
| Abnormal BMI (< 18.5 or ≥ 25 kg/m2) | 0.551 | 0.220–1.377 | 0.202 |
| Diabetic mellitus | 2.103 | 0.799–5.539 | 0.132 |
| Hypertension | 1.951 | 0.804–4.734 | 0.139 |
| Serum haemoglobin < 12 | 1.132 | 0.415–3.086 | 0.809 |
| Serum albumin < 3.5 | 1.921 | 0.654–5.645 | 0.235 |
| Serum creatinine ≥ 1.4 | 0.390 | 0.045–3.384 | 0.393 |
| PCRT | 1.379 | 0.529–3.596 | 0.511 |
| Adjuvant chemotherapy | 0.608 | 0.233–1.583 | 0.308 |
| uLAR (versus LAR) | 1.547 | 0.538–4.454 | 0.418 |
| CDI-positive | 6.922 | 2.115–22.654 | 0.001 |
PCRT, preoperative chemoradiotherapy; uLAR, ultra-low anterior resection; LAR, low anterior resection; CDI, Clostridium difficile infection. *Leakage was assessed for anastomosis between colon and rectum.