TABLE 1.

Neonatal acute kidney injury diagnostic criteria.

AKI stage	Serum creatinine (SCr) criteria	Urine output criteria (hourly rate)
0	No change in SCr or SCr rise < 0.3 mg/dL	≥0.5 ml/kg/h
1	SCr rise ≥ 0.3 mg/dL rise within 48 h or SCr rise ≥ 1.5–1.9 × baseline SCra	<0.5 ml/kg/h × 6–12 h
2	SCr rise ≥ 2.0–2.9 × baseline SCra	<0.5 ml/kg/h for >12 h
3	SCr rise ≥ 3 × baseline SCra or SCr ≥ 2.5 mg/dLb or Kidney support therapy utilization	<0.3 ml/kg/h for ≥24 h or Anuria for ≥12 h

Modified, neonatal Kidney Disease: Improving Global Outcomes (KDIGO) criteria. ^aBaseline SCr defined as lowest previous SCr value. ^bSCr value of 2.5 mg/dL represents glomerular filtration rate of <10 mL/min/1.73 m². SCr, serum creatinine; mg/dL, milligrams per deciliter; h, hours. Adapted from Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Workgroup. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2012;2:1–138.