Table 2.
Baseline patient-level CCTA findings.
|
Overall (n = 376) |
Primary endpoint (+) (n = 15) | Primary endpoint (-) (n = 361) | p-value | |
|---|---|---|---|---|
| CAD-RADS classification | ||||
| 0 | 76 (20.2 %) | 1 (6.7%) | 75 (20.8%) | 0.182 |
| 1 | 110 (29.3%) | 1 (6.7%) | 109 (30.2 %) | 0.049 |
| 2 | 39 (10.3%) | 3 (20.0%) | 36 (10.0%) | 0.212 |
| 3 | 74 (19.7%) | 1 (6.7%) | 73 (20.2%) | 0.196 |
| 4A | 44 (11.7%) | 3 (20.0%) | 41 (11.4%) | 0.308 |
| 4B | 21 (5.6%) | 3 (20.0%) | 18 (5.0%) | 0.0131 |
| 5 | 12 (3.2%) | 3 (20.0%) | 9 (2.5%) | <0.001 |
| ≥3 | 151 (40.2 %) | 10 (66.7%) | 141 (39.1%) | 0.033 |
| Location of obstructive CAD | ||||
| LMCA | 8 (2.1 %) | 1 (6.7%) | 7 (1.9%) | |
| LAD | 105 (27.9 %) | 9 (60.0%) | 96 (26.6%) | |
| LCX | 57 (15.2 %) | 5 (33.3%) | 52 (14.4%) | |
| RCA | 59 (15.7 %) | 6 (40.0%) | 53 (14.7%) | |
| %NCP volume, % | 21.7 (6.52) | 23.4 (6.53) | 21.7 (6.52) | 0.302 |
| %CP volume, % | 1.03 (2.82) | 6.22 (9.17) | 0.82 (1.97) | <0.001 |
| %LAP volume, % | 1.35 (0.98) | 1.92 (1.28) | 1.33 (0.96) | 0.023 |
| CACS, Agatston unit | 17 (0–166) | 67 (0–390) | 4.8 (0–108) | <0.001 |
| EAV, ml | 124.0 (52.0) | 134.9 (51.0) | 123.5 (51.2) | 0.4 |
| Abdominal visceral adipose tissue area, cm2 | 101.3 (57.4) | 110.4 (66.0) | 100.9 (57.1) | 0.53 |
Variables were expressed as n (%), mean (SD) or median (interquartile range, IQR). CACS = coronary artery calcium score, CAD, coronary artery disease; CCTA, coronary computed tomography angiography; EAV, epicardia adipose tissue volume; LAD, left anterior ascending artery; LCX, left circumflex artery; LMCA, left main coronary artery; RCA, right coronary artery; NCP, non-calcified plaque; CP, calcified plaque; LAP, low attenuation non-calcified plaque.