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. 2022 Apr 7;13:848849. doi: 10.3389/fpsyt.2022.848849

Table 6.

Association between components of frailty and incident depressive symptoms not depressed at baseline.

Follow-up period Model 1
HR (95%CI)
Wald, df P-value Model 2
HR (95%CI)
Wald, df P-value Model 3
HR (95%CI)
Wald, df P-value Model 4
HR (95%CI)
Wald, df P-value
2011 → 2013 Weakness
N = 839 No (795) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (44) 1.334
(0.694, 2.566)
0.747,1 0.387 1.29
(0.662, 2.516)
0.56,1 0.454 1.224
(0.623, 2.403)
0.343,1 0.558 1.186
(0.602, 2.334)
0.243,1 0.622
Slowness
No (679) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (160) 1.519
(1.046, 2.204)
4.828,1 0.028 1.617
(1.101, 2.376)
5.995,1 0.014 1.549
(1.048, 2.288)
4.829,1 0.028 1.597
(1.078, 2.366)
5.454,1 0.020
Weight loss
No (766) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (73) 1.631
(0.983, 2.705)
3.592,1 0.058 1.632
(0.976, 2.73)
3.488,1 0.062 1.587
(0.944, 2.667)
3.042,1 0.081 1.510
(0.895, 2.548)
2.38,1 0.123
Exhaustion
No (705) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (134) 1.410
(0.944, 2.104)
2.82,1 0.093 1.394
(0.928, 2.093)
2.556,1 0.110 1.352
(0.897, 2.037)
2.079,1 0.149 1.353
(0.897, 2.041)
2.082,1 0.149
Low activity
No (738) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (101) 0.972
(0.604, 1.563)
0.014,1 0.907 1.006
(0.619, 1.634)
0.001,1 0.982 0.997
(0.612, 1.625)
0,1 0.991 1.023
(0.627, 1.668)
0.008,1 0.929
2011 → 2015 Weakness
N = 788 No (750) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (38) 2.205
(1.146, 4.243)
5.61,1 0.018 2.098
(1.078, 4.083)
4.755,1 0.029 2.103
(1.068, 4.142)
4.625,1 0.032 2.080
(1.055, 4.104)
4.467,1 0.035
Slowness
No (639) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (149) 1.006
(0.687, 1.474)
0.001,1 0.975 1.047
(0.708, 1.547)
0.052,1 0.820 0.992
(0.667, 1.477)
0.002,1 0.969 0.998
(0.670, 1.487)
0.000,1 0.993
Weight loss
No (722) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (66) 0.986
(0.574, 1.693)
0.003,1 0.958 0.994
(0.575, 1.72)
0,1 0.984 1.017
(0.585, 1.77)
0.004,1 0.951 0.992
(0.568, 1.735)
0.001,1 0.979
Exhaustion
No (656) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (132) 1.853
(1.264, 2.716)
9.997,1 0.002 1.961
(1.326, 2.898)
11.394,1 0.001 1.936
(1.302, 2.877)
10.674,1 0.001 1.928
(1.297, 2.867)
10.542,1 0.001
Low activity
No (698) Ref (1.000) Ref (1.000) Ref (1.000) Ref (1.000)
Yes (90) 1.478
(0.941, 2.32)
2.878,1 0.090 1.618
(1.016, 2.576)
4.113,1 0.043 1.566
(0.979, 2.505)
3.495,1 0.062 1.582
(0.988, 2.533)
3.652,1 0.056

Model 1, unadjusted; Model 2, adjusted for age, sex, educational levels, marital status, live place; Model 3, adjusted for age, sex, educational levels, marital status, live place, current smoking, alcohol drinking, activities, chronic diseases; Model 4, adjusted for age, sex, educational levels, marital status, live place, current smoking, alcohol drinking, activities, chronic diseases, BMI.