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. 2022 Jan 11:1–6. doi: 10.1017/ice.2022.13

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© The Author(s) 2022

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means subject to acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Fig. 3. — Percent of incident COVID-19 hospitalizations with severe disease (SpO2 <90% and/or oxygen supplementation ≥2L) from March 1, 2020, to November 22, 2021. Points represent observed percentages of incident hospitalizations with documented oxygen saturation (SpO₂) <90% or receipt of ≥2 L oxygen supplementation (circles) or use of dexamethasone (squares) in each week of the study period, among unvaccinated (blank) or vaccinated (cross) patients. Lines (respectively, shaded areas) represent smoothed estimates (respectively, their 95% confidence intervals) over time based on Poisson regression with a penalized spline term, among unvaccinated (solid) and vaccinated (dashed) patients.