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. 2022 Apr 7;9:780174. doi: 10.3389/fmed.2022.780174

TABLE 5.

Relationship between AST/ALT and baseline demographic characteristics (7-years follow up).

Variables AST/ALT ≤ 1.05 AST/ALT > 1.06 X2 or t P
(n = 42) (n = 52)
Age, y 73.10 ± 7.833 71.37 ± 6.863 1.140 0.257
Education, y 12.60 ± 5.147 12.02 ± 3.534 0.642 0.523
Basline of MoCA 22.68 ± 8.589 22.75 ± 5.216 –0.404 0.687
Male, n (%) 12 (28.6) 20 (38.5) 1.102 0.384
Somker, n (%) 6 (14.3) 8 (15.4) 0.022 1.000
Drinker, n (%) 5 (11.9) 11 (21.2) 1.407 0.279
Tea drinker, n (%) 20 (47.6) 18 (34.6) 1.631 0.214
Take exercise, n (%) 24 (57.1) 38 (73.1) 2.267 0.128
Hypertension, n (%) 22 (52.4) 31 (59.6) 0.494 0.534
Diabetes, n (%) 5 (11.9) 9 (17.3) 0.535 0.566
Follow-up cognitive decline, n (%) 14 (32.7) 37 (70.8) 14.152 < 0.001*
The total protein, mmol/L 71.82 ± 4.160 73.38 ± 5.350 –1.485 0.141
Total bilirubin,mmol/L 10.78 ± 4.181 11.89 ± 11.88 –0.557 0.579
Creatinine, mmol/L 71.37 ± 15.16 71.73 ± 18.27 –0.093 0.926
Total cholesterol, mmol/L 5.12 ± 0.909 5.05 ± 1.260 0.316 0.752
Triglycerides, mmol/L 1.95 ± 1.228 1.50 ± 0.816 1.995 0.070
High density lipoprotein, mmol/L 1.19 ± 0.227 1.29 ± 0.400 –1.515 0.134
Low density lipoprotein, mmol/L 3.18 ± 0.765 3.37 ± 1.019 –0.927 0.356
Fasting plasma glucose, mmol/L 5.46 ± 1.861 5.03 ± 0.887 1.407 0.163
Follow-up of MOCA 21.67 ± 3.989 19.19 ± 5.089 2.629 0.010*
The whole brain volume, mm3 1478368.65 1420594.39 1.906 0.060
Left hippocampus, mm3 3687.22 ± 427.73 3529.82 ± 397.59 1.849 0.068
Right hippocampus, mm3 3903.44 ± 471.33 3668.94 ± 520.276 2.287 0.024*
Left amygdala, mm3 1537.50 ± 213.47 1462.60 ± 237.98 1.604 0.112
Right amygdala, mm3 1667.49 ± 222.83 1594.92 ± 277.75 1.394 0.167

MoCA, Montreal Cognitive Assessment; ALT, Alanine transferase; AST, Glutamyl transferase. *p < 0.05.