TABLE 5.
Relationship between AST/ALT and baseline demographic characteristics (7-years follow up).
| Variables | AST/ALT ≤ 1.05 | AST/ALT > 1.06 | X2 or t | P |
| (n = 42) | (n = 52) | |||
| Age, y | 73.10 ± 7.833 | 71.37 ± 6.863 | 1.140 | 0.257 |
| Education, y | 12.60 ± 5.147 | 12.02 ± 3.534 | 0.642 | 0.523 |
| Basline of MoCA | 22.68 ± 8.589 | 22.75 ± 5.216 | –0.404 | 0.687 |
| Male, n (%) | 12 (28.6) | 20 (38.5) | 1.102 | 0.384 |
| Somker, n (%) | 6 (14.3) | 8 (15.4) | 0.022 | 1.000 |
| Drinker, n (%) | 5 (11.9) | 11 (21.2) | 1.407 | 0.279 |
| Tea drinker, n (%) | 20 (47.6) | 18 (34.6) | 1.631 | 0.214 |
| Take exercise, n (%) | 24 (57.1) | 38 (73.1) | 2.267 | 0.128 |
| Hypertension, n (%) | 22 (52.4) | 31 (59.6) | 0.494 | 0.534 |
| Diabetes, n (%) | 5 (11.9) | 9 (17.3) | 0.535 | 0.566 |
| Follow-up cognitive decline, n (%) | 14 (32.7) | 37 (70.8) | 14.152 | < 0.001* |
| The total protein, mmol/L | 71.82 ± 4.160 | 73.38 ± 5.350 | –1.485 | 0.141 |
| Total bilirubin,mmol/L | 10.78 ± 4.181 | 11.89 ± 11.88 | –0.557 | 0.579 |
| Creatinine, mmol/L | 71.37 ± 15.16 | 71.73 ± 18.27 | –0.093 | 0.926 |
| Total cholesterol, mmol/L | 5.12 ± 0.909 | 5.05 ± 1.260 | 0.316 | 0.752 |
| Triglycerides, mmol/L | 1.95 ± 1.228 | 1.50 ± 0.816 | 1.995 | 0.070 |
| High density lipoprotein, mmol/L | 1.19 ± 0.227 | 1.29 ± 0.400 | –1.515 | 0.134 |
| Low density lipoprotein, mmol/L | 3.18 ± 0.765 | 3.37 ± 1.019 | –0.927 | 0.356 |
| Fasting plasma glucose, mmol/L | 5.46 ± 1.861 | 5.03 ± 0.887 | 1.407 | 0.163 |
| Follow-up of MOCA | 21.67 ± 3.989 | 19.19 ± 5.089 | 2.629 | 0.010* |
| The whole brain volume, mm3 | 1478368.65 | 1420594.39 | 1.906 | 0.060 |
| Left hippocampus, mm3 | 3687.22 ± 427.73 | 3529.82 ± 397.59 | 1.849 | 0.068 |
| Right hippocampus, mm3 | 3903.44 ± 471.33 | 3668.94 ± 520.276 | 2.287 | 0.024* |
| Left amygdala, mm3 | 1537.50 ± 213.47 | 1462.60 ± 237.98 | 1.604 | 0.112 |
| Right amygdala, mm3 | 1667.49 ± 222.83 | 1594.92 ± 277.75 | 1.394 | 0.167 |
MoCA, Montreal Cognitive Assessment; ALT, Alanine transferase; AST, Glutamyl transferase. *p < 0.05.