Table 3.
Univariate Analysis in Factors Influencing pCR of T3 Rectal Cancer.
| Patient | X2 | P | |||
|---|---|---|---|---|---|
| pCR | Non-pCR | ||||
| Gender | Male | 15 | 62 | ||
| Female | 5 | 25 | 0.112 | 0.737 | |
| EMD (mm) | EMD | 6.14 ± 3.56 | 7.21 ± 2.85 | 76.513 | 0.150 |
| T3 | T3a + b | 4 | 26 | ||
| subcategory | T3c + d | 16 | 61 | 4.274 | 0.118 |
| PTI (%) | <50 | 15 | 42 | ||
| ≥50 | 5 | 45 | 14.665 | 0.001 | |
| cN category | (−) | 4 | 5 | ||
| (+) | 16 | 82 | 1.745 | 0.187 | |
| MRF status | (−) | 17 | 60 | ||
| (+) | 3 | 27 | 8.318 | 0.026 | |
| Direction* | Anterior | 1 | 8 | ||
| Lateral | 18 | 71 | |||
| Posterior | 1 | 7 | 0.643 | 0.725 | |
|
Length**
(cm) |
<5 | 13 | 48 | ||
| ≥5 | 7 | 39 | 0.641 | 0.423 | |
|
Distance***
(cm) |
<5 | 15 | 56 | ||
| ≥5 | 5 | 31 | 5.842 | 0.054 | |
|
CEA
(ng/ml) |
<5.2 | 5 | 25 | ||
| ≥5.2 | 15 | 52 | 0.303 | 0.582 | |
|
CA19-9
(U/ml) |
<27 | 3 | 19 | ||
| ≥27 | 17 | 68 | 1.913 | 0.167 | |
Direction*, The main direction of tumor invasion; Length**, The tumor length measured on MRI; Distance***, The distance from the anal verge to the edge of the tumor; EMD, The extramural depth of tumor invasion; PTI, The percentage of tumor invasion; MRF, mesorectal fascia.