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. 2022 Apr 7;12:855308. doi: 10.3389/fonc.2022.855308

Figure 4.

Figure 4

Reduced diversity of TCR clones in ERBB2d16-high patients. (A) Shannon index was lower in the ERBB2d16-high patients (n = 20) compared with the ERBB2d16-low patients (n = 20). (B) Clonality index was higher in the ERBB2d16-high patients (n = 20) compared with the ERBB2d16-low patients (n = 20). (C) Evenness index was higher in the ERBB2d16-high patients (n = 20) compared with the ERBB2d16-low patients (n = 20). (*p < 0.05, **p < 0.001, ***p < 0.0001). Δ16 low: ERBB2d16/ERBB2 ratio < 0.88; Δ16 high: ERBB2d16/ERBB2 ratio ≥ 0.88. ERBB2: human epidermal growth factor receptor-2; ERBB2d16: ERBB2ΔEx16; TCR: T cell receptor.