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. 2022 Apr 7;16:842814. doi: 10.3389/fnins.2022.842814

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Copyright © 2022 Wu, Zhai, Liang, Chen, Lin, Ma, Huang, Zhao, Liang, Zhao, Fang, Fang, Chen and Wang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of 27-OHC on Aβ production and elimination. 24-OHC, 24 (S) -hydroxycholesterol; 27-OHC, 27-hydroxycholesterol; ABCA1, ATP-binding cassette A1; ApoE, apolipoprotein E; APP, amyloid precursor protein; BBB, blood-brain barrier; Chol, cholesterol; Gadd153, growth arrest and DNA damage-induced gene 153; IDE, insulin-degrading enzyme; LRP1, LDL receptor-like protein 1; and RAGE, receptor for advanced glycation end products.