Table 3.
Antigen distribution and HLA-A restrictions of 105 HBV T cell epitopes used in the clinical detection of HBV-specific T cells.
| HLA-A allotype | Allele frequency | HBV CD8+ T cell epitope peptides | Total | |||
|---|---|---|---|---|---|---|
| HBsAg | HBeAg (covering HBcAg) | HBpol | HBx | |||
| A1101 | 22.4% | P101, P103, P107, P108, P13, P14, P38, P39, P40, P41 | P109, P118, P1, P23, P4, P31, P42, P43 | P105, P106, P110, P10, P15, P16, P46, P25, P33 | P17, P47, P48, P18, P83, P84 | 33 |
| A2402 | 15.3% | P19, P51, P20, P78, P108, P103, P71, P72, P95 | P23, P22, P53, P52, P111, P31, P11, P67, P74 | P24, P56, P25, P55, P106, P119 | P63, P93, P100, P26 | 28 |
| A0201 | 13.9% | P72, P78, P13, P7, P2, P8, P38, P77, P19 | P1, P67, P11, P31, P32, P66, P88, P96, P118, P52, P74 | P68, P10, P33, P55, P34, P99, P98, P89, P90 | P18, P47, P12, P36 | 33 |
| A0207 | 9.5% | P71, P72, P2, P51, P108, P73, P103 | P31, P74, P67, P118, P1, P111, P52, P53,P42 | P56, P10, P76 | P35 | 20 |
| A3303 | 8.1% | P78, P77, P59, P58, P79, P122 | P43, P4, P80 | P10, P55, P81, P82 | P84, P83 | 15 |
| A0206 | 6.1% | P7, P2 | P1, P67, P66, P88 | P68, P10, P99, P16, P89 | P69, P70 | 13 |
| A3001 | 5.2% | P85, P86 | P87, P88, P118 | P91, P90, P89 | P93, P94, P92, P17 | 12 |
| A0203 | 3.9% | P95, P7, P39 | P96, P11, P1, P31, P67, P97 | P99, P98, P34, P68, P33, P76 | P100, P35 | 17 |
| A3101 | 3.4% | P58, P40, P59 | P43, P60 | P61, P62 | P63, P84, P64 | 10 |
| A1102 | 2.3% | P40, P41, P72, P108, P13, P101, P102, P103 | P111, P4, P42, P104, P109 | P106, P16, P105 | P17, P47, P48, P83, P121 | 21 |
| A0101 | 2.2% | P72, P71, P108, P6 | P111 | P112, P113 | P114 | 8 |
| A2601 | 1.8% | P115, P116 | P118, P117 | P119, P113, P120 | P121 | 8 |
| A0301 | 1.4% | P71, P72, P101, P108, P13, P107 | P43, P109, P104 | P110, P106 | P17, P48, P63, P47 | 15 |