TABLE 1.
Demographic and clinical characteristics of participants
| Patients | Adult patients | Pediatric patients |
|---|---|---|
| n (female:male) | 103 (45:58) | 65 (34:31) |
| Median age, years (range) | 39 (19– 68) | 13 (5– 18) |
| Seizure focus laterality (left:right) | 49:53a | 41:20a |
| Seizure focus lobe, temporal/frontal/other | 87/8/8 | 32/11/22 |
| Abnormal clinical MRI, n (%)b | 56 (54.4%) | 54 (83.1%) |
| MTS/MTS+ | 42 | 12 |
| MCD/FCD | 5 | 18 |
| Neoplasm and cystic lesions | 5 | 11 |
| Vascular/encephalomalacia | 4 | 13 |
| Controls | Adult controls | Pediatric controls |
| n (female:male) | 92 (44:48) | 17 (7:10) |
| Mean age, years (range) | 37.5 (19– 71) | 11 (5– 18) |
Note: A total of 277 participants contributed to 442 acquisition runs.
Abbreviations: FCD, focal cortical dysplasia; MCD, malformations of cortical development; MRI, magnetic resonance imaging; MTS, mesial temporal sclerosis.
One adult patient and four pediatric patients had uncertain laterality and were excluded from secondary analysis.
MTS/MTS+: MTS and MTS plus another relevant lesion, such as FCD; MCD/FCD: MCD including mostly FCD but also polymicrogyria, nodular heterotopias, tuberous sclerosis, and hemimegalencephaly. Neoplasm and cystic lesions: low-g rade tumors, cystic calcified or noncalcified lesions such as infection sequelae deemed relevant to the patient’s diagnosis of epilepsy. Vascular/encephalomalacia: stroke and perinatal ischemic lesions, cavernous malformations, arteriovenous malformations deemed relevant to patient’s diagnosis of epilepsy.