Corapcioglu 2006.

Methods	RCT Open 2004‐2005
Participants	Number: 28 patients (50 episodes) Age: med 8.4 ± SD 5.2
Interventions	piperacillin‐tazobactam 80+10mg/kgX4 versus cefepime 50mg/kgX3
Outcomes	Infection‐related mortality (at least 7 days after discontinuation of treatment) Clinical failure, fever duration Drug modifications Adverse events
Notes	Turkey
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	Consecutive randomization
Allocation concealment?	Unclear risk	No description
Blinding? All outcomes	High risk	Blinding not used
Incomplete outcome data addressed? All‐cause mortality	Unclear risk	All‐cause mortality not assessed
Incomplete outcome data addressed? Treatment failure	Low risk
Free of other bias?	High risk	Unit of randomization = episodes; patients to episodes ratio 0.56