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. 2010 Nov 10;2010(11):CD005197. doi: 10.1002/14651858.CD005197.pub3

Figuera 2001.

Methods RCT
 Open
 1994‐1996
Participants Number: 150 patients Age: mean 38.3; range 16‐73
Interventions imipenem 500mgX4
 versus
 piperacillin‐tazobactam 4.5grX4
Outcomes Overall mortality ‐ at end of treatment
 Clinical and microbiological failure
 Drug modifications
 Adverse events
Notes Spain
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk No description
Allocation concealment? Unclear risk No description
Blinding? 
 All outcomes High risk Blinding not used
Incomplete outcome data addressed? 
 All‐cause mortality High risk 9% dropouts
Incomplete outcome data addressed? 
 Treatment failure High risk 9% dropouts
Free of other bias? Low risk