Liang 1990.

Methods	RCT Open 1988‐1989
Participants	Number: 92 patients (103 episodes) Age: mean 38, range 16‐76
Interventions	ceftazidime 1grx3 versus imipenem 500mg x 4
Outcomes	Overall and infection‐related mortality ‐ at end of treatment Clinical and microbiological failure Superinfection Drug modifications Adverse events
Notes	Hong‐Kong
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Low risk	Table of random numbers
Allocation concealment?	Unclear risk	No description
Blinding? All outcomes	High risk	Blinding not used
Incomplete outcome data addressed? All‐cause mortality	High risk	3% dropouts
Incomplete outcome data addressed? Treatment failure	High risk	3% dropouts
Free of other bias?	High risk	Unit of randomization = episodes; patients to episodes ratio 0.89