| Methods |
RCT
Assessor blinded |
| Participants |
Number: 104 patients (149 episodes)
Age: med 6, range 5m‐19y |
| Interventions |
cefepime 50mg/kg x 3
versus
ceftazidime 50mg/kg x 3 |
| Outcomes |
Overall and infection‐related mortality ‐ at 30 days after end of treatment
Clinical and microbiological failure
Superinfection
Drug modifications
Adverse events |
| Notes |
USA |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
No description |
| Allocation concealment? |
Unclear risk |
No description |
| Blinding?
All outcomes |
High risk |
Response was determined by an independent blinded reviewer |
| Incomplete outcome data addressed?
All‐cause mortality |
Low risk |
|
| Incomplete outcome data addressed?
Treatment failure |
High risk |
Number of dropouts (11%) known per study group |
| Free of other bias? |
Low risk |
|
