Oztoprak 2010.

Methods	RCT Open
Participants	Number: 127 episodes, 84 patients (120 episodes assessed) Age: mean 45.6
Interventions	piperacillin‐tazobactam 4.5grX3 versus meropenem 1grX3 or imipenem 500mgX4
Outcomes	Overall mortality at 30 days Clinical failure Adverse events
Notes	Turkey
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Low risk	computer‐generated random‐number program
Allocation concealment?	Unclear risk	No description
Blinding? All outcomes	High risk	Blinding not used
Incomplete outcome data addressed? All‐cause mortality	Low risk	Mortality data for all patients, but reported per episode and not per patient's first episode
Incomplete outcome data addressed? Treatment failure	High risk	5% dropouts
Free of other bias?	High risk	Unit of randomization = episodes; patients to episodes ratio 0.66. Mortality reported per patient.