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. 2010 Nov 10;2010(11):CD005197. doi: 10.1002/14651858.CD005197.pub3

Reich 2005.

Methods RCT
Open
1997‐2001
Participants Number: 236 patients
Age: meropenem med 44 range (18–70); piperacillin‐tazobactam 44 (20–63)
Interventions meropenem 1grX3
versus
piperacillin‐tazobactam 4.5grX3
Outcomes Clinical failure, fever duration
Notes MC Germany
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk No description
Allocation concealment? Low risk Sealed envelopes attached to sequentially numbered patient documentation folders (opaque not mentioned)
Blinding? 
 All outcomes High risk No blinding used
Incomplete outcome data addressed? 
 All‐cause mortality Unclear risk Outcome not reported
Incomplete outcome data addressed? 
 Treatment failure High risk 2% dropouts
Free of other bias? Low risk