Uygun 2009.

Methods	Quasi‐randomized trial Open 2005‐2006
Participants	Number: 69 patients (127 episodes) Age: median 4.2 range (0.3‐18)
Interventions	piperacillin‐tazobactam 80+10mg/kgX4 vs cefepime 50mg/kgX3
Outcomes	All‐cause and infection‐related mortality (at end of hospital stay) Clinical and microbiological failure, fever duration and hospital stay Drug modifications Adverse events
Notes	Turkey
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	High risk	Alternation
Allocation concealment?	High risk
Blinding? All outcomes	High risk	Blinding not used
Incomplete outcome data addressed? All‐cause mortality	Low risk
Incomplete outcome data addressed? Treatment failure	Low risk
Free of other bias?	High risk	Unit of randomization = episodes; patients to episodes ratio 0.54