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. 2010 Nov 10;2010(11):CD005197. doi: 10.1002/14651858.CD005197.pub3

Vural 2010.

Methods RCT
Open
2005‐2006
Participants Number: 63 patients (99 episodes)
Age: med 5 range (2‐14)
Interventions piperacillin‐tazobactam 80+10mg/kgX4
versus
imipenem‐cilastatin 15mg/mgX4
Outcomes All‐cause and infection‐related mortality (during the neutropenic episode)
Clinical failure
Drug modifications
Adverse events
Notes Turkey
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk No description
Allocation concealment? Unclear risk No description
Blinding? 
 All outcomes High risk Blinding not used
Incomplete outcome data addressed? 
 All‐cause mortality Low risk  
Incomplete outcome data addressed? 
 Treatment failure Low risk  
Free of other bias? High risk Unit of randomization = episodes; patients to episodes ratio 0.64