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. 2022 Apr 7;13:850221. doi: 10.3389/fphar.2022.850221

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Copyright © 2022 Huang, Chen, Zhang, Chen, Zhao, Feng, Lei and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cluster analysis plots (A) 28-days-motality (x-axis) and ICU length of stay (y-axis) (B) 28-days-motality (x-axis) and hospital length of stay (y-axis) (C) 28-days-motality (x-axis) and SOFA score at day 7 after interventions (y-axis) (D) 28-days-motality (x-axis) and procalcitonin level at day 7 after interventions (y-axis) (E) 28-days-motality (x-axis) and serum lactate level at day 7 after interventions (y-axis); WM, Western Medicine; SF, Shenfu injection; SM, Shenmai injection; SGM, Shengmai injection; XBJ, Xuebijing injection; HQ, Huangqi injection; SQFZ, Shenqifuzheng injection. Interventions with the same color belong to the same cluster, and interventions located in the lower-left corner indicate the optimal therapy for two different outcomes while located in the upper-right corner indicate the worst therapy.