Table 3.

Patient-Reported Outcomes at Baseline (T0), Week 5 (T1), and One Month after Chemoradiation Therapy (T2) and Differences (Betas) between Time Points

	T0 mean (SD), n = 20	T1 mean (SD), n = 20	T2 mean (SD), n = 19	T1–T0 β	p	T2–T0 β	p	T2–T1 β	p
HADS-depression	2.54 (2.88)	5.85 (3.47)	4.89 (4.03)	3.31	0.0000	2.20	0.0075	−1.11	0.0522
HADS-anxiety	4.05 (3.85)	3.81 (3.11)	3.68 (3.38)	−0.24	0.6047	−0.43	0.4898	−0.19	0.7485
FACT-HN	117.88 (20.48)	97.69 (20.27)	104.21 (23.72)	−20.19	0.0000	−13.37	0.0040	6.82	0.0226
MDASI-HN	1.47 (1.34)	2.99 (1.62)	2.01 (1.50)	1.52	0.0001	0.45	0.2074	−1.07	0.0000

FACT-HN, Functional Assessment of Cancer Therapy-Head and Neck; HADS, Hospital Anxiety and Depression Scale; MDASI-HN, MD Anderson Symptom Inventory-Head and Neck; SD, standard deviation.