FIG. 2.
Wound sections. Representative MT (model 1–3) and H&E (model 4) stained sections derived from each of the wound models. Model 1. WT control (C57BL/6J) and obese type 2 DM (B6.Cg-lepob/J, ob/ob) mice with excisional wounds 7 days postinjury. Model 2. Young and old wild-type control (C57BL/6J) mice on a HFD with punch biopsy wounds. For this model representative images of day 14 postinjury are presented although sections from days 3,7,14, and 21 postinjury were analyzed. Model 3. Wild-type control (C57BL/6J) mice with pressure ulcers 14 days postinjury. To delay healing, NEP was injected subcutaneously in the wound area in a subgroup of mice. Model 4. WT control (C57BL/6J) mice with burn wounds 9 weeks postinjury. A subgroup of mice was treated with Dasatinib. The wound area is indicated with dotted lines. HFD, high fat diet; WT, wild-type. Color images are available online.