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. Author manuscript; available in PMC: 2022 Apr 21.
Published in final edited form as: Obesity (Silver Spring). 2021 Apr;29(Suppl 1):S9–S24. doi: 10.1002/oby.23086

Figure 5.

Figure 5

Combination therapy can produce greater weight loss: doubling the dose of either phentermine or topiramate does not double the weight loss, whereas adding phentermine to topiramate does give additive weight loss.