TABLE 1.

Susceptibilities of gram-positive isolates to daptomycin and vancomycin

Species (no. of isolates tested)	MIC (μg/ml)
	Daptomycin			Vancomycin
	50%	90%	Range	50%	90%	Range
MRSA (54)	1	1	0.5–1	2	2	1–2
MSSA (27)	0.25	1	0.06–1	0.5	1	0.5–2
MRSS (29)	0.5	1	0.25–2	2	4	2–4
S. pneumoniae (penicillin susceptible; MIC, ≤0.06 μg/ml (16)	0.03	0.125	0.015–0.5	0.125	0.25	0.125–0.25
S. pneumoniae (penicillin intermediate; MIC, 0.12 to 1.0 μg/ml) (21)	0.25	1	0.008–1.0	0.25	0.5	0.008–1.0
S. pneumoniae (penicillin resistant; MIC, ≥2 μg/ml) (24)	0.5	1	0.015–1.0	0.25	0.5	0.125–0.5
S. pyogenes (10)	0.015	0.125	0.008–0.5	0.25	0.5	0.25–1
E. faecalis (vancomycin susceptible) (20)	1	1	0.25–2	1	2	0.5–2
VREF (23)	1	2	0.5–2	>64	>64	>64