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. 2022 Apr 7;13:851967. doi: 10.3389/fendo.2022.851967

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Copyright © 2022 Biswas, Coyle, Chen, Gostimir, Gonder and Chakrabarti

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pearson correlation analyses between serum and vitreous samples. When comparing between serum and vitreous samples, significant correlations were observed for (A) ANRIL, (B) H19, (C) HOTAIR, (E) MALAT1, (H) WISPER and (I) ZFAS1, which suggests that the expressions of these lncRNAs can be reflected from the serum and vitreous of patients with DR. Although we did find significant correlations between serum and vitreous concentrations of (D) HULC, (F) MEG3, and (G) MIAT, including a larger sample size may further help confirm the relationships between these markers and sample types [p<0.05 was considered significant; dotted lines represent 95% confidence intervals. N= 10 for control group and N= 11 for diabetic group; and normalized to β-actin]. DR, diabetic retinopathy.