Table 4.

HbA1c Spearman’s rank correlation coefficient.

Spearman's rank correlation coefficient ρ (Control n = 7, Patient n = 51)
	ANRIL	H19	HOTAIR	HULC	MALAT1	MEG3	MIAT	WISPER	ZFAS1
Control n = 7
ρ	0.36	-0.49	0.68	0.07	0.00	-0.74	0.14	0.34	0.52
P-value	0.427	0.268	0.090	0.878	1.000	0.058	0.758	0.452	0.229
Patient n = 51
ρ	0.022	0.083	-0.063	-0.044	-0.143	-0.075	-0.054	-0.178	-0.106
P-value	0.879	0.564	0.662	0.760	0.318	0.602	0.705	0.211	0.459
Combined P and C, n=58
ρ	0.237	0.103	0.164	0.167	0.034	-0.157	0.094	0.022	0.133
P-value	0.074	0.439	0.219	0.210	0.803	0.238	0.481	0.869	0.320

Spearman's rank correlation coefficients of lncRNAs and HbA1c expression. To obtain p-values, t-statistic was used.

Method:

1. lncRNA and HbA1c amounts for each sample was ranked using RANK.AVG () function.

2. Step 1 was done for control (n=7), for all patients with available HbA1c values (n=51 – some patients missing this information), and for the combination of both (n=58).

3. Correlation between the two ranks for each sample was calculated using CORREL() function.

4. T-statistic, degree of freedom was calculated for each correlation to obtain p-value using TDIST() function.