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. 2022 Apr 7;13:876555. doi: 10.3389/fimmu.2022.876555

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Copyright © 2022 Guo, Semerci, De Assis, Kayisli, Schatz, Steffensen, Guzeloglu-Kayisli and Lockwood

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SARS-CoV-2 spike protein immunostaining in placental villi from women tested positive for Covid-19. Endothelial cells and trophoblastic layers display strong to weak SARS-CoV-2 spike protein immunoreactivity in placental sections from COVID-19 infected mothers (n=3), but not in cells in placental sections from non-infected mothers (n=3). Inset picture represents negative control incubated with non-immune IgG_2a at the same monoclonal IgG_2a primary antibody concentration. PS, Placental specimen; Original magnification: 40X.