Table 1.

Experimental settings on immune cell function/fate that are associated with CD36 dual functions

Cell type	Cell environment	Species	Cell function/Fate	Reference
Monocytes	In vitro culture	Human	Differentiation to macrophages	Huh et al. (1996)
Monocytes	In vitro culture	Human	Differentiation to DCs	Szatmari et al. (2004)
Macrophages	In vitro culture	Human and mouse	Phagocytosis	Greenberg et al. (2006)
Microglia and macrophages	In vitro culture	Mouse	Cytokine, chemokine secretion and ROS production	El Khoury et al. (2003)
Macrophages	In vitro culture	Human and mouse	Cell motility reduction	Park et al. (2009)
Macrophages	In vitro culture	Mouse	M2-like polarization	Vats et al. (2006)
Macrophages	In vitro culture	Mouse	Inflammasome activation and IL-1β secretion	Sheedy et al. (2013)
DCs	In vitro culture	Human	Efferocytosis	Urban et al. (2001)
Cancer stem cells	Tumor	Human and mouse	Self-renew	Hale et al. (2014)
Leukemic stem cells	Gonadal adipose tissue	Human and mouse	Evade chemotherapy	Ye et al. (2016)
Nonclassical monocytes	Peripheral blood vessels	Mouse	Patrolling along blood vessels	Marcovecchio et al. (2017)
Macrophages	Aorta	Mouse	Foam cell formation	Febbraio et al. (2000); Rahaman et al. (2006)
Macrophages	Aorta	Human and mouse	Mitochondrial ROS production, glycolytic switch	Chen et al. (2019)
Macrophages	Tumor	Human and mouse	Fatty acid oxidation	Su et al. (2020)
Macrophages	Adipose tissue	Mouse	Inflammatory paracrine loop	Kennedy et al. (2011)
MDSCs	Tumor	Human and mouse	Immunosuppression	Xin et al. (2021)
Treg cells	Tumor	Human and mouse	TME adaptation and immunosuppression	Wang et al. (2020)
CD8 T cells	Tumor	Human and mouse	Ferroptosis	Ma et al. (2021); Xu et al. (2021)
B cells	Blood	Human and mouse	Autophagy and humoral immune responses	He et al. (2021)