Skaer 1993.

Methods	‐ Randomised controlled trial ‐ Adequate randomisation ‐ Blinding of patients, administrators and outcome assessors: inadequate ‐ No description of losses to follow‐up ‐ Intention‐to‐treat analysis ‐ Groups were similar at the start of the study ‐ Groups were equally provided of care ‐ Overall judgement of quality: medium
Participants	‐ Single centre study in the USA ‐ 258 Type 2 diabetes patients recruited from primary care services ‐ Participants : intervention I1 (79), I2 (53), I3 (48), control (78) ‐ Sex: I1 (F: 54, M: 25), I2 (F: 31, M:22), I3 (F:29, M: 19), control (F: 49, M: 29) ‐ Mean age: I1 (53.6 yrs, SD 7.7), I2 (51.8 yrs, SD 8.6), I3 (52.3 yrs, SD 8.4), control (51.7 yrs, SD 7.8) ‐ Treatment modality: oral hypoglycaemic agents: I1: 79, I2: 53, I3: 48, control: 78
Interventions	To discern the effect of mailed prescription‐refill reminders (I1), specialised packaging (I2), or a combination of both (I3) on prescription refill compliance and health service utilisation.
Outcomes	MPR (medication prescription refill), number of days' supply obtained over 360 days of the trial.
Notes	Previously untreated type 2 diabetes patients, prescribed glyburide bd, no utilisation of nurse care for prior 3 months.