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. 2022 Mar 8;90(4):e00056-22. doi: 10.1128/iai.00056-22

FIG 2.

FIG 2

The killing of PMNs by WT and isogenic mutant strains. (A) Infection of PMNs with indicated strains for 2 h with an MOI of 10. PMN lysis was measured by LDH release. Data show mean ± SEM of PMNs isolated from 6 independent blood donors. *, P ≤ 0.05; **, P ≤ 0.01 by RM one-way ANOVA with Tukey’s multiple-comparison tests. (B) Intoxication of PMNs with cell-free supernatants from indicated strains. The PMN viability was measured by CellTiter. Data show mean ± SEM of PMNs isolated from 6 independent blood donors. *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001 compared to WT by RM one-way ANOVA with Dunnett’s multiple-comparison tests.