| Why carry out this study? |
| COVID-19 is a global pandemic, and effective therapies are needed to reduce the burden on the health system. |
| Interferon therapy may be effective in the clinical management of SARS-CoV-2 as interferons play an important role in immune response. |
| What was learned from the study? |
| Synthesizing existing data on interferon therapy for COVID-19 is challenging, as previous trials have used methods, outcome measures and interferon subtypes that vary greatly. |
| Standardized outcomes are needed in future studies to enable comparisons and draw conclusions about the effectiveness of interferon therapy in the treatment of COVID-19. |
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