Fig 7. Upregulation of the inflammasome components in ZIKV-infected macrophages.

Total RNA was prepared at various time points p.i. from THP-1 and RAW264.7 cells infected with 0.1 MOI of ZIKV for realtime RT-PCR to measure mRNA transcript numbers of pro-caspase-1 (A & B) and NLRP3 (C & D). The experiments were performed in triplicates and the data were shown as mean+SD, analysed by unpaired Students t-test. *, P<0.05; **, P<0.01. ns, no significance.