Fig 5. Comparison of escape profiles in the stem helix-HR2 region (SH-H).

(A) and (B) Data are shown as described in Fig 3. (C) Logo plots for participant 352 (a convalescent macaque) and M21 (a vaccinated human) showing the effect of specific mutations on antibody binding at each site. The comparison between these samples had an escape similarity score closest to the median value for all pairwise convalescent macaque vs. vaccinated human comparisons and thus can be considered representative of the similarity between these groups. The 352 –M21 comparison is shown in red on (B).