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. 2022 Apr 4;18(4):e1010416. doi: 10.1371/journal.ppat.1010416

Table 2. Serological and virological status of animals exposed to HTLV-1WT and HTLV-1p12KO.

Treatment HTLV-1WT HTLV-1p12KO
α-CD8/NK α-CD8 Clodrosome/Encapsome α-CD8/NK α-CD8 Clodrosome
Seropositive 3/3 3/3 1/5** 4/4 1/4 1/5
Seroindeterminate 0/3 0/3 4/5 0/4 3/4 4/5
Seronegative 0/3 0/3 0/5 0/4 0/4 1/5
PCR gag +2/3 +3/3 +3/3* +4/4 +3/4 +4/4
PCR orf-I +3/3 +3/3 +2/3* +4/4 +3/4 +4/4
PCR gag/orf-I +2/3 +3/3 +2/3* +4/4 +2/4 +4/4

* Only three animals analyzed: P651, R257, H28J.

** Unsustained seroconversion

Animals ZJ22, Z151, and HPM treated with clodrosome, and ZJ58 treated with encapsosome, were not sacrificed and were enrolled in a subsequent study.