Table 2. Clinical spectrum of disease in LSL-Kras^G12D/+; LSL-Trp53^R172H/+; Pdx-1-Cre; Slc6a14^−/− (KPCS) mice.

Sr. no.	Age (days)	Sex/animal ID	Histological diagnosis	Metastasis								Ascites
				Liver	Lung	Diaphragm	Spleen	Stomach	Intestine	Kidneys	Adrenals
1	118	F7	Invasive ductal carcinoma (moderately differentiated)	N	N	N	N	N	N	N	N	N
2	181	M1	Invasive ductal carcinoma (well differentiated)	N	Y	N	N	N	N	N	N	N
3	229	M2	Invasive ductal carcinoma (poorly differentiated)	Y	N	N	N	N	N	N	N	N
4	199	F1	Invasive ductal carcinoma (moderate to poorly differentiated)	N	Y	Y	N	N	N	Y	N	Y
5	232	F1	Invasive ductal carcinoma (moderate to poorly differentiated)	N	N	Y	N	Y	N	N	N	Y
6	204	F2	Invasive ductal carcinoma (well differentiated)	Y	N	N	N	N	N	N	N	N
7	118	F7	Tissues not evaluated due to necrosis. No apparent tumor	*	*	*	*	*	*	*	*	*
8	121	M1	No carcinoma identified	N	N	N	N	N	N	N	N	N
9	160	M3	High-grade sarcoma of the gluteal region	Y	Y	N	N	N	N	N	N	N
10	176	M4	Sarcomatoid carcinoma	N	N	N	N	N	N	N	N	N
11	142	M5	Invasive ductal carcinoma (poorly differentiated)	N	N	N	N	Y	N	N	N	N
12	214	M7	Invasive ductal carcinoma (mostly poorly differentiated)	N	N	Y	N	N	N	N	N	Y
13	177	F1	Positive for malignancy; lesional tissue has spindle cell morphology	N	N	N	N	N	N	N	N	Y
14	224	F2	Invasive ductal carcinoma	Y	N	N	N	N	N	N	N	N
15	138	M4	Invasive ductal carcinoma	Y	Y	N	N	N	N	N	N	N
16	168	F7	Invasive ductal carcinoma (moderately differentiated)	N	N	N	N	N	N	N	N	N
17	278	F2	No carcinoma identified	N	N	N	N	N	N	N	N	N
Total			11/17	5/16	4/16	3/16	0/16	2/16	0/16	1/16	0/16	4/16

Y, yes; N, no; *, tissue not evaluated.