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. 2022 Mar 25;50(7):3799–3816. doi: 10.1093/nar/gkac183

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Rec8 cohesin complex shapes chromosomes into a structure suitable for its alignment. (A) Hi-C contact maps of three chromosomes for the indicated strains, prepared from the cells 0 and 2.5 h after entry into meiosis. The color scale on the right represents the percent ranking of contact scores. (B) The alignment index for the indicated strains at meiotic prophase (2.5 h after meiosis induction) is shown as the value along with a black vertical line in the Hi-C contact map of chromosome 1.