Figure 9.
DNaseI-SEC-SAXS analysis of c-Myc-12 sequence. (A) SAXS scattering (Log-linear scale) of non-digested c-Myc-12 with overlaid fits of the all-parallel stacked or hairpin models and their weighted residuals. (B) Best-fitting hairpin model fit into the DAMMIF/N refined scattering envelope along with its schematic representation. (C) SAXS scattering (Log-linear) of DNaseI-digested c-Myc-12 sequence with overlaid fit of the all-parallel model (fully intact) and its weighted residuals. (D) c-Myc-12 all-parallel eight stack model fit into the post-digest DAMMIF/N refined scattering envelope and its schematic representation. (E) Pair-distance distribution functions of pre-digestion (gray) and post-digestion (red) particles.