TABLE 3.
Dose (mg/kg/day) | % Attainment of response
|
||||||||
---|---|---|---|---|---|---|---|---|---|
S. pneumoniae
|
S. aureus
|
Enterococcal spp.
|
|||||||
Stasis | Log drop (3 log10 units) | 90% Emax | Stasis | Log drop (2 log10 units) | 90% Emax | Stasis | Log drop (1 log10 unit) | 90% Emax | |
6 | 100 ± 0.0 | 99.9 ± 0.009 | 95.87 ± 0.07 | 91.64 ± 0.2 | 71.79 ± 1.89 | 34.25 ± 0.68 | 99.70 ± 0.11 | 99.41 ± 0.02 | 58.14 ± 2.82 |
9 | 100 ± 0.0 | 100 ± 0.0 | 97.71 ± 0.02 | 96.83 ± 0.08 | 85.10 ± 0.84 | 50.74 ± 0.84 | 99.93 ± 0.004 | 99.77 ± 0.009 | 74.84 ± 0.59 |